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Symbol
Name
ID
Foxc2
forkhead box C2
MGI:1347481
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Conjunctivitis
Abnormal cardiovascular system morphology
Ventricular septal defect
Tetralogy of Fallot
Patent ductus arteriosus
Varicose veins
Arrhythmia
Abnormality of the pulmonary vasculature
Disease(s) Associated with FOXC2
lymphedema-distichiasis syndrome

Mouse Phenotypes
cardiovascular system phenotype
abnormal blood vessel morphology
abnormal fourth pharyngeal arch artery morphology
abnormal third pharyngeal arch artery morphology
abnormal aortic arch morphology
aortic arch coarctation
interrupted aortic arch, type b
absent glomerular endothelium fenestra
decreased glomerular capillary number
dilated glomerular capillary
thin myocardium
perimembraneous ventricular septal defect
ventricular septal defect
pericardial effusion
abnormal lymph circulation
intracranial hemorrhage
glomerulus hemorrhage
spinal hemorrhage
Availability Mouse Genotype
Foxc2tm1.2Tsku/Foxc2tm1.2Tsku
Foxc2tm1Blh/Foxc2tm1Blh
Foxc2tm1Miu/Foxc2tm1Miu
Foxc2tm1Miu/Foxc2+
Foxc2tm1.1Miu/Foxc2tm1.1Miu
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Foxc2tm1.1Miu/Foxc2tm1.1Miu
Tg(Tek-cre)1Ywa/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory